Delta-8-THC and Other Obscure Cannabinoids | Narcotica #63
By cacpodcast.comRecently I spoke with Troy Farah on the podcast Narcotica all about cannabinoid science, delta-8-THC, issues around vaping and legalization, and more! Thanks to the team at Narcotica for allowing us to share this episode! I hope you enjoy! Stay curious, and take it easy.
About this Episode of Narcotica:
“Nearly half the U.S. population now have access to adult-use cannabis. Marijuana is a medicine, if it’s cultivated or extracted right, and millions of people find relief or pleasure from this fantastic plant. But as legalization accelerates, regulations have struggled to keep up. Most experts and maybe many consumers would agree that cannabis is not well regulated or could use some improvements.
Meanwhile, new cannabinoids like delta-8-THC, THC-O and more are hitting the streets, licit and illicit. This is a rapidly changing environment, which is far beyond THC and CBD, the two most well-known drugs in marijuana. It leaves a lot of questions: Are these ‘new’ cannabinoids safe? What do they do in the body? What about vaping them?
Narcotica co-host Troy Farah speaks with Jason Wilson of Medford Oregon, host of the Curious About Cannabis podcast, and author of the book of the same name, which can be found at CACpodcast.com. Jason is a biologist and science educator that has been studying the biochemistry of the cannabis plant and cannabis-derived products for nearly a decade. Jason has done work with groups like the International Institute for Cannabinoids (ICANNA) and serves as a member on the board of directors for the Oregon Cannabis Education and Resource Center.
Follow Jason on Twitter @AboutCannabis
If you liked this episode, here are others you might enjoy:
Episode 53: A Life of Getting Lit with Tommy Chong
Episode 49: Salvia: Psychedelic Oddity (Plus, Canada’s Emerging Psilocybin Scene)
Episode 25: Banning Kratom Will Escalate the Opioid Overdose Crisis with Walter Prozialeck
Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Garrett Farah
Music: Glass Boy / Done With Fish
Intro voice: Jenny Schaye
Image: Flickr — Willpower Studios // edit: Troy Farah
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BTS #61 Markus Roggen PhD on Optimizing Cannabis Extraction and Research
In this behind-the-scenes episode we sit down with chemist Dr. Markus Roggen of Delic Labs (formerly Complex Biotech Discovery Ventures) to talk about his journey to help Cannabis processors and researchers optimize their processes, make better products and uncover better data about Cannabis and cannabinoids.
Throughout the conversation we talk about his journey coming from Germany to California and what it was like getting involved in Cannabis research. We also discuss many of the different research projects that he has been involved in and the insights that he and his teams have been able to gain about extraction science and cannabinoid chemistry. Finally we discuss some of the work that Delic Labs is doing with psychedelics and what they hope to uncover about nature’s mind manifesting molecules.
You can learn more about Delic Labs at: https://deliclabs.com/
Stay curious and take it easy!
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BTS #43 Murphy Murri (Returns!) on CRC, Color in Extracts, Concentrate Remediation
In this behind-the-scenes conversation we are rejoined with extraction technologist and Cannabis educator Murphy Murri to talk all about CRC aka “Color Remediation Cartridges”. CRC has gained a lot of buzz, both positive and negative, in recent years as extractors experiment with refinement techniques that manipulate the appearance of the extract. The concept of “colorless” Cannabis extracts was largely popularized by The Clear years ago, and now has become commonplace. But what is CRC? And what is happening to these extracts when their color is “remediated”? And does CRC present any risks to consumers or extraction technicians?
Murphy Murri provides a common sense take on CRC for anyone wanting to wrap their minds around this popular topic.
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BTS #39 Arno Hazekamp PhD on Cannabis Chemovars, Controversies, and the Need for Better Education
In this behind-the-scenes interview we are joined by Arno Hazekamp, PhD. Arno is based out of the Netherlands and has been researching Cannabis since 2001. He is probably most famous for proposing the concept of Cannabis chemovars to replace the idea of “strains”. His work has primarily focused on examining the chemical constituents of Cannabis and Cannabis products including Cannabis teas, Rick Simpson Oil (RSO), and more. He has also published numerous papers on other topics like Cannabis sterilization via gamma irradiation, review papers on human clinical research around Cannabis, and many more.
Arno shares my passion for science communication and science education, which came through very clearly in this conversation. We discussed many different topics over the course of the two hours including common Cannabis misconceptions, evidence for therapeutic applications of Cannabis, how to think about “strains” and indica/sativa vernacular, the best way to make Cannabis tea, the importance of writing scientific papers with a lay audience in mind, and a whole lot more!
Connecting with Arno was a delight and I look forward to talking to him again in the future. I hope you enjoy this conversation as much as I did.
Learn more about Arno’s work at https://hazekamp.info/
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BTS #38 Jeffrey Raber PhD on The Werc Shop, Cannabis Testing, Delta-8 THC Impurities, Product Standardization
In this behind-the-scenes episode we talk with Dr. Jeff Raber of The Werc Shop, a Cannabis and cannabinoid science and technology company that began testing Cannabis products in California back in 2010. Our conversation explores Dr. Raber’s background in biochemistry, the turbulent history of Cannabis testing labs, how Cannabis companies began leveraging Cannabis test results to improve products, impurities found in delta-8 THC products, the future of The Werc Shop and more!
Learn more about The Werc Shop: https://thewercshop.com/
The Curious About Cannabis Podcast is produced by Natural Learning Enterprises, a mission driven company focused on enhancing critical thinking skills and public scientific literacy about life and the natural world. If you enjoy Curious About Cannabis, consider checking out some of these other programs by Natural Learning Enterprises:
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- Toadstool’s Treasures (www.ToadstoolsTreasures.com)
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- GardenWild (www.GardenWild.org)
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- Serious About Psychedelics (www.SeriousAboutPsychedelics.com)
Learn more about Natural Learning Enterprises at www.NaturalEDU.com
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BTS #32 Mark Scialdone PhD on Cannabis Chemistry History, Hydrogenated Cannabinoids, Science and Art
In this behind-the-scenes episode we sit down with Mark Scialdone PhD, a chemist responsible for inventing hydrogenated cannabinoid acids, semi-synthetic cannabinoids that could be effective at battling certain types of cancer. We discuss the history of cannabinoid science, controversy around cannabinoid boiling points, how Mark learned from his research with catnip essential oil hydrogenation and how he adapted the technology for Cannabis essential oil, the importance of balancing science with art, the future of Cannabis research, his role in helping the American Chemical Society’s Cannabis Chemistry subdivision get started, and much more.
This episode was cut for time. To listen to the extended 2+ hour version, visit www.Patreon.com/CuriousAboutCannabis
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BTS #29 Kyle Boyar on Microbiological Testing, Cannabinoid Hyperemesis Syndrome, LIMS
In this behind-the-scenes episode we sit down with Kyle Boyar, vice chair and scholarship chair for the Cannabis Chemistry subdivision of the American Chemical Society and Director of Product Science at TagLeaf. We talked about the ways Cannabis testing labs test Cannabis samples for microbiological contaminants, how microbiological testing can go wrong, other issues facing Cannabis testing, controversy around a medical condition called Cannabinoid Hyperemesis Syndrome (CHS), and more!
This conversation was cut to fit our new 1.5 hour limit. To listen to the entire 2 hour conversation, join our community on Patreon at www.Patreon.com/CuriousAboutCannabis
Enjoy and stay curious!
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BTS #28 Jacqueline von Salm PhD on Cannabis Terpenes, Drugs From Nature, Chemical Ecology
In this behind-the-scenes episode we sit down with organic chemist Jackie von Salm PhD (@terp_queen_phd on Instagram), who was a recent winner of the ElSohly award given to outstanding researchers in the Cannabis space. Her team recently discovered the presence of a terpene common only among certain varieties of Cannabis, which is not tested for currently among most Cannabis testing labs and has largely been excluded from the discussion when talking about categorizing Cannabis varieties by chemical profile. We also discuss the process of discovering natural products suitable for drug development, how chemistry is interconnected with ecology and psychology, what she wants to see from future Cannabis research and much more!
Jackie is a co-founder and CSO of the company Psilera Bioscience which is dedicated to exploring the potential of psychoactive natural products to treat mental health disorders.
Learn more about Psilera Bioscience at www.psilera.com
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BTS #27 Austin Flohrschutz MS of TruPotency on CBD Product Fraud, Safety Testing, Salvia Research
In this behind-the-scenes episode, we talk with Austin Flohrschutz, the Science Director for TruPotency.com, a CBD retailer that performs extensive third party testing on CBD products to screen for fraudulent or mislabeled products. At the time that we spoke, Austin informed me that they had tested 400 products, and 30% of those products passed testing. The vast majority of failures were for mislabeled potency. Around 0.5% failed for contaminants like heavy metals or residual solvents. Through this conversation we discuss the extent of CBD product fraud in the market, what TruPotency has seen regarding CBD product quality, issues related to cannabinoid testing, research into the psychedelic Salvinorin A from Salvia divinorum and implications for alternative opioid therapies, and much more.
Enjoy and stay curious!
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BTS #18 Kevin McKernan of Medicinal Genomics on Cannabis Genetics, GMO Cannabis, Pest Resistance
In this behind-the-scenes (BTS) episode we sit down with Kevin McKernan, the founder of Medicinal Genomics, who has been working for years on mapping and understanding the Cannabis genome. Our 2 hour conversation spanned many topics including basic misunderstandings about genetics, the genes responsible for cannabinoid production in Cannabis, how genes sometimes do unexpected things, how Cannabis genes are related to pest resistance, philosophical and ethical issues related to genetic modification of organisms and much more.
The pre-print research article referenced in this conversation can be found here: https://www.medicinalgenomics.com/breakthrough-cannabis-genomics-study/
Medicinal Genomics: www.medicinalgenomics.com
Kannapedia: www.kannapedia.net
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