Endocannabinoid System

The Science Behind CBG: A Pharmacist’s Perspective with Codi Peterson PharmD MS

Explore the fascinating world of Cannabigerol (CBG) in the latest episode of our podcast! We are joined by our friendly neighborhood pharmacist – Dr. Codi Peterson. As we delve into the hot topic of CBG, we cover its effects on the body and compare it to other medications. We also take an unexpected detour to discuss the influence of AI like ChatGPT in Cannabis education. Join us as we ponder the future of Cannabis content, engage in lively conversation, and learn a lot more about this promising cannabinoid. Tune in now!

#CBG #CannabisCommunity #Cannabinoids #HempProducts #PharmacyInsights #CannabisEducation #ChatGPT #FutureOfCannabisContent #CannabisPodcast #CuriousAboutCannabis #CodiPeterson #JasonWilsonMS #HempScience #Cannabigerol #CannabisIndustry #CannabisCommunity

Seeing Through The Smoke: Separating Cannabis Facts from Fiction with Peter Grinspoon, MD | BTS 92

In this behind-the-scenes episode we catch up with physician and medical Cannabis educator Peter Grinspoon, MD to talk about the ways in which Cannabis is misunderstood – both by the anti-Cannabis camps and the pro-Cannabis camps. We talk about the clinical data around medical Cannabis, what issues Cannabis has demonstrated efficacy in treating, the limitations of medical Cannabis and more.

We also spend some time diving into Peter’s background, talking about his late father Lester Grinspoon, MD who authored a landmark book entitled Marihuana Reconsidered which was published in 1971 and paved the way for the medical Cannabis movements that would follow. We also discussed Peter’s brother Danny’s struggle with cancer, which claimed his life at the age of 15, and the role Cannabis played in enhancing Danny’s quality of life before he died. Later in life Peter would struggle with a grueling opiate addiction which he would later go on to write about in his 2016 book Free Refills: A Doctor Confronts His Addiction. Toward the end of the show we talk about what it was like growing up around famed scientist and science communicator Carl Sagan, who was a good friend of the Grinspoon family and also a Cannabis user.

Peter just released a new book entitled Seeing Through The Smoke: A Cannabis Specialist Untangles The Truth About Marijuana available now.

This was a special episode for me, personally, because Peter’s work, the work of his father, and the work of Carl Sagan all had big impacts on how I came to think about Cannabis and science education. I hope you enjoy!

#CannabisEducation #MedicalCannabis #MedicalMarijuana #CannabisIndustry #CannabisCommunity #Cannabinoids #Addiction #CarlSagan #LesterGrinspoon #PeterGrinspoon #Cancer

Remembering Raphael Mechoulam’s Legacy on Cannabis Science with Mark Scialdone, PhD | BTS 91

In this special episode we get together with chemist and Cannabis science educator Mark Scialdone, PhD to talk about the passing of “the godfather of Cannabis science”, Raphael Mechoulam, PhD. After his passing, many media and news outlets failed to accurately portray Mechoulam’s contributions or his place in the grand story of Cannabis science – so Dr. Scialdone and I decided to try to do our part to set the record straight. Along the way we spin off into talking about a variety of other topics like delta-8-THC synthesis from CBD, common misunderstandings around Cannabis chemistry, why the boiling point of THC is almost always incorrectly reported, and more.

The Quest for the CB3 Receptor and Beyond with Viola Brugnatelli, PhD | BTS 89

Is there a CB3 receptor?

In this episode we catch up with Italian endocannabinoid system researcher and neuropharmacologist Viola Brugnatelli, PhD to discuss her work investigating the activity of orphaned G-protein coupled receptors (GPCRs) like GPR55, GPR18, GPR92, and others.

We also discuss Viola’s decision to focus her energy on educating the healthcare community and others about the science of Cannabis through her company Cannabiscientia which just published a great resource for health care providers called The Principles of Clinical Cannabinology.

To learn more about Cannabiscientia, visit https://cannabiscientia.com/

#cannabis #cannabinoids #cb3 #ecs #endocannabinoidsystem #cannabiscientia #cannabisscience #cannabinoidpharmacology #medicalcannabis #medicalmarijuana #curiousaboutcannabis

Cannabis and the Convergence of Neurodivergence with Miyabe Shields PhD | BTS 87

Disclaimer: In this episode, we discuss some heavy topics that touch on mental health struggles and suicidal ideation. None of the information in this episode or any other Curious About Cannabis episode should be considered medical advice. All of our content is for educational and entertainment purposes only.

In this raw behind-the-scenes episode I had the chance to catch up with endocannabinoid system researcher and science communicator Miyabe Shields, PhD. We spent much of our time together discussing the convergence of Cannabis, mental health, and neurodivergence – addressing many of the taboos and social stigmas associated with altering consciousness and treating the mind with Cannabis.

This is almost certainly just the beginning of a series of conversations that Miyabe and I will be having as we continue to unpack their fascination with the endocannabinoid system and natural products science – so stay tuned for more!

#Cannabis #CannabisResearch #Neurodiversity #Neurodivergent #Spectrum #Consciousness #CannabisEducation #MedicalCannabis #CannabisForMentalHealth #Psychology #NaturalProducts #CuriousAboutCannabis

Cannabinoid Science: Past, Present and Future (Southern Oregon University Lecture, 2021)

The history of cannabinoid science tells a fascinating story that many people are really unfamiliar with. In this lecture, which I gave for Southern Oregon University back in October of 2021, I chart some of the basic series of events that led to the discovery of CBD, THC, cannabinoid receptors, the endocannabinoid system, and the endocannabinoidome.

The video associated with this lecture is available on the Curious About Cannabis YouTube at http://www.youtube.com/@curiousaboutcannabis

The 2023 Curious About Cannabis Master Class is coming up! Spend 6 months diving into a Cannabis science crash course with me and over a dozen special guests! Register today at http://www.masterclasscannabis.com

Cannabis Quality is More Than THC or Terpenes with Adie Rae PhD | BTS #78

What does Cannabis quality mean to you? Is it all about THC? Is it all about the terps?

In this behind-the-scenes episode we caught up with pharmacologist and researcher Dr. Adie Rae from Oregon, USA to talk primarily about the results of her recent publication “The Nose Knows: Aroma, but Not THC Mediates the Subjective Effects of Smoked and Vaporized Cannabis Flower” which revealed that subjective aroma enjoyment correlates more with positive Cannabis experiences than THC or terpene concentrations. We also discussed Dr. Rae’s prior and current research on the interactions between the endocannabinoid system and opioids, the need to re-evaluate how we define “quality” in the Cannabis industry, the importance of organoleptic training for medicinal herbs, and more!

Adie Rae is a neuroscientist known for her extensive expertise on cannabis. She is an Assistant Scientist at Legacy Research Institute, and adjunct faculty at Washington State University. Her human and preclinical research is focused on pain management, addiction, and harm reduction. Adie has published in top academic journals under the surname Wilson-Poe, and she is passionate about the interaction between cannabis and opioids. Adie serves as the Vice-Chair of the Oregon Cannabis Commission, and she is a long-standing member of the International Cannabinoid Research Society. Dr. Rae also co-founded the consulting and technology firm Smart Cannabis. Follow her on Instagram: @dr.adie

You can learn more about Dr. Rae and her work at https://www.smartcannabis.life/

Link to “Nose Knows” study: https://www.mdpi.com/2813-1851/1/2/8

The Endocannabinoid Jam (“Interstellar Chillhop Vibes” by Mattjs Muller Remixed feat. Curious About Cannabis

Enjoy this chillhop jam dedicated to endocannabinoids and the endocannabinoidome!

Base song is “Interstellar Chillhop Vibes” by Mattjs Muller which was remixed by Jason Wilson featuring samples from The Curious About Cannabis Podcast, including the following episodes:

BTS #35 Vincenzo di Marzo PhD,

BTS #5 Ethan Russo MD, and

BTS #4 Kevin Spelman PhD

Delta-8-THC and Other Obscure Cannabinoids | Narcotica #63

Recently I spoke with Troy Farah on the podcast Narcotica all about cannabinoid science, delta-8-THC, issues around vaping and legalization, and more! Thanks to the team at Narcotica for allowing us to share this episode! I hope you enjoy! Stay curious, and take it easy.

About this Episode of Narcotica:

“Nearly half the U.S. population now have access to adult-use cannabis. Marijuana is a medicine, if it’s cultivated or extracted right, and millions of people find relief or pleasure from this fantastic plant. But as legalization accelerates, regulations have struggled to keep up. Most experts and maybe many consumers would agree that cannabis is not well regulated or could use some improvements.

Meanwhile, new cannabinoids like delta-8-THC, THC-O and more are hitting the streets, licit and illicit. This is a rapidly changing environment, which is far beyond THC and CBD, the two most well-known drugs in marijuana. It leaves a lot of questions: Are these ‘new’ cannabinoids safe? What do they do in the body? What about vaping them?

Narcotica co-host Troy Farah speaks with Jason Wilson of Medford Oregon, host of the Curious About Cannabis podcast, and author of the book of the same name, which can be found at CACpodcast.com. Jason is a biologist and science educator that has been studying the biochemistry of the cannabis plant and cannabis-derived products for nearly a decade. Jason has done work with groups like the International Institute for Cannabinoids (ICANNA) and serves as a member on the board of directors for the Oregon Cannabis Education and Resource Center.

Follow Jason on Twitter @AboutCannabis

If you liked this episode, here are others you might enjoy:
Episode 53: A Life of Getting Lit with Tommy Chong
Episode 49: Salvia: Psychedelic Oddity (Plus, Canada’s Emerging Psilocybin Scene)
Episode 25: Banning Kratom Will Escalate the Opioid Overdose Crisis with Walter Prozialeck

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Garrett Farah
Music: Glass Boy / Done With Fish
Intro voice: Jenny Schaye
Image: Flickr — Willpower Studios // edit: Troy Farah

Kevin Spelman PhD on Herbs to Compliment or Counteract Cannabis Effects | BTS #64

In this behind-the-scenes conversation we meet up again with molecular biologist Kevin Spelman, PhD to talk about medicinal herbs that can either compliment or counteract the effects of Cannabis in different ways. Along the way we spin out into all sorts of other topics like discussing “adaptogens”, allostatic vs. homeostatic systems in the body, issues around placebo effects and Cannabis, potential dangers concerning inhaling high concentrations of terpenes, thinking critically about drug-drug interactions with Cannabis, and more!

Learn more about Dr. Spelman’s show The Spelman Report: Phytopharmacology Review at www.thespelmanreport.com

Check out Dr. Spelman’s prior appearance on the show in Curious About Cannabis Behind-the-Scenes Episode #4: https://cacpodcast.com/bts-04-kevin-spelman-phd-on-the-endocannabinoid-system-plant-synergies-and-dietary-supplement-research/

Stay curious, and take it easy!

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