HHC, THCP, and Beyond with Westley Cruces of Colorado Chromatography
By cacpodcast.comYou may have noticed that your local gas station has started selling products marketed like Cannabis products with promises that they are legal ways to get you high without THC. No, we haven’t gone back in time. This isn’t 1999 and no, you’re not reading one of those “legal bud” ads in the back of the High Times magazine. This is 2024 and we are seeing a re-emergence of synthetic cannabinoids, particularly THC analogues, now presumably legal under the guise of the 2018 Farm Bill.
Colorado Chromatography is one of the leading labs responsible for producing and studying these new cannabinoids on the block, like HHC, H4CBD, THCP, and others. In this conversation we sit down with the Chief Science Officer of and co-founder of Colorado Chromatography, Westley Cruces, to talk about their journey learning about these molecules, the results from preliminary safety studies on HHC, evidence of fraud in delta-8 and THCP products, and more!
Learn more about Colorado Chromatography: https://coloradochromatography.com/
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Is Acetone Lurking in Your Terpenes? and Other Cannabis Science Musings feat. Jeff Raber, PhD
We kick off 2024 catching up with Dr. Jeff Raber of The Werc Shop to talk about Cannabis quality, Cannabis potency testing fraud, THC inflation, acetone showing up in Cannabis extracts, preparing young scientists for working in the Cannabis industry, the launch of The Werc Shop’s ENTOUR brand and more!
How do we fix the lab testing fraud issue in the Cannabis industry?
Why is acetone showing up in terpene-rich Cannabis samples?
How can young scientists prepare for the brutal realities of working for a startup Cannabis company?
We explore these questions and more in this episode of The Curious About Cannabis Podcast!
Learn more about ENTOUR at www.entourbrand.com
Learn more about The Werc Shop at www.thewercshop.com
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What’s In a Toke? Exploring the Chemistry of Cannabis Smoke and More with Dr. Riley Kirk | BTS #79
Why does smoking Cannabis deliver unique effects compared to vaping or ingesting Cannabis? Why are social media platforms banning Cannabis educators from talking about the science of Cannabis? We have questions!
In this behind-the-scenes episode I sat down with Dr. Riley Kirk (@cannabichem) from Real Isolates, the company behind the Cannabis smoke extract product called Smokenol, to talk about the chemistry of Cannabis smoke (and lots of other cool natural products science!). In this conversation we discuss some of the unique cannabinoids that show up in Cannabis smoke and what Dr. Kirk has learned during her time studying the transformations of cannabinoids like CBD.
We also discussed her struggle to share Cannabis science education with the world due to the antagonistic nature of social media toward Cannabis content. Dr. Kirk has been shadow banned and de-platformed from social media sites like Instagram and TikTok for discussing basic Cannabis science and cannabinoid pharmacology. We dive into why these issues have real-world adverse effects for anyone curious about Cannabis and what Cannabis educators should know before they rush to their Reels or Stories to talk about Cannabis.
The conversation rounds off with a dive into Dr. Kirk’s love for plants where we talk about her favorite non-Cannabis medicinal plants and the exciting things we can learn when we apply the lens of Cannabis science to other natural products.
Profound Naturals: https://www.profoundnaturals.com/
Smokenol: https://smokenol.com/
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Catching Up with Murphy Murri on Benzene, Medusa Stones, and Owning the Quality of Your Lab | BTS #75
In this behind-the-scenes episode we caught up with Murphy Murri for an extended discussion about the current state of the Cannabis industry, extraction supply chain quality issues, medusa stones, mushroom extraction and more.
Medusa stones are concentrated lumps of cannabinoids that, rather than having a clear “diamond” appearance, has a chalky appearance. And like you might expect, the “diamond” disintegrates after being handled, turning into a sticky, chalky mess. So what causes the medusa stone phenomenon in Cannabis extracts? During this conversation, Murphy breaks down the phenomenon and the controversy surrounding the hunt for the cause behind these disappointing creations.
Due to some technical difficulties on the day of recording, this discussion was recorded on Zoom instead of our usual platform, resulting in some compromised audio quality.
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Sniffing Out the Skunk in Cannabis with TJ Martin of Abstrax Tech | BTS #74
In this behind-the-scenes episode we caught up with TJ Martin of Abstrax Tech to discuss their research into Cannabis extracts and the chemistry that impacts the plant’s aromas and flavors. We talk about their discovery of a family of sulfur compounds in Cannabis that are largely responsible for the skunk smell of Cannabis. We also discussed their prior research into vape pen additives and what kinds of compounds may be emitted from heated vape pen additives.
To learn more about Abstrax Tech, visit www.abstraxtech.com
Abstrax is a flavor and fragrance manufacturer that specializes in cannabis and hop raw materials, terpenes, and aroma compound research to innovate terpene driven product formulations that shape consumer packaged goods. Abstrax specializes in botanical research, ingredient manufacturing and formulation science with a specific focus on terpene research.
T.J. Martin graduated with a B.S. in Chemistry from CSU Polytechnic Pomona. He gained experience with a wide array of analytical techniques and research applications by collaborating with groups in the fields of chemistry, solid state physics, green chemistry, materials science, and polymer science. Currently T.J. is the VP of Research and Development at Abstrax where he creates custom flavor solutions and research fundamental and applied facets of cannabis science via Abstrax Labs.
Research Articles Mention in This Episode:
Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography
Iain W. H. Oswald, Marcos A. Ojeda, Ryan J. Pobanz, Kevin A. Koby, Anthony J. Buchanan, Josh Del Rosso, Mario A. Guzman, and Thomas J. Martin. ACS Omega 2021 6 (47), 31667-31676. http://doi.org/10.1021/acsomega.1c04196
Characterization of Vaping Emission Products from Commonly Used Vape Juice Diluents
Huanhuan Jiang, C. M. Sabbir Ahmed, Thomas J. Martin, Alexa Canchola, Iain W. H. Oswald, Jose Andres Garcia, Jin Y. Chen, Kevin A. Koby, Anthony J. Buchanan, Zixu Zhao, Haofei Zhang, Kunpeng Chen, and Ying-Hsuan LinChemical Research in Toxicology 2020 33 (8), 2157-2163. http://doi.org/10.1021/acs.chemrestox.0c00174
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Want a Successful Cannabis Business? Be a Crock Pot, Not a Microwave! with Alisia and Chris Ratliff | BTS #72
In this behind-the-scenes episode we join up with Alisia Ratliff once again, this time joined by her husband Chris as we catch up and learn about the work they are doing in their consulting agency, Victus Consulting Ventures. We dive into a number of topics including the science of surfactants for Cannabis products, lessons learned from years of Cannabis business consulting, issues facing Cannabis cultivators that try to scale, and more!
The takeaway? Be a crock pot, not a microwave.
Learn more about Victus Consulting Ventures at https://www.victus-cv.com/
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Inspiring a Passion for Extraction Science and Technology with John MacKay, PhD | BTS #70
In this behind-the-scenes episode of The Curious About Cannabis Podcast we drop in with natural products extraction expert John MacKay, PhD. Dr. MacKay has been involved in both extraction and analytical technology for decades and has gained a lifetime of experience that he is eager to share with others. An avid educator and lifelong learner himself, Dr. MacKay teaches about Cannabis and mushroom extraction through the John MacKay Institute of Extraction Technology where he offers engaging hands-on workshops to teach the fundamentals of natural products extraction as applied to Cannabis and mushrooms. He is also a professor through several universities where he teaches about biochemistry. John is a wealth of information and has a solid sense of humor, so I hope you enjoy this conversation!
Learn more about the John MacKay Institute of Extraction Technology: https://www.extractioninstitute.com/
Learn more about Synergistic Technologies Associates: https://www.synergistictechassociates.com/
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BTS #61 Markus Roggen PhD on Optimizing Cannabis Extraction and Research
In this behind-the-scenes episode we sit down with chemist Dr. Markus Roggen of Delic Labs (formerly Complex Biotech Discovery Ventures) to talk about his journey to help Cannabis processors and researchers optimize their processes, make better products and uncover better data about Cannabis and cannabinoids.
Throughout the conversation we talk about his journey coming from Germany to California and what it was like getting involved in Cannabis research. We also discuss many of the different research projects that he has been involved in and the insights that he and his teams have been able to gain about extraction science and cannabinoid chemistry. Finally we discuss some of the work that Delic Labs is doing with psychedelics and what they hope to uncover about nature’s mind manifesting molecules.
You can learn more about Delic Labs at: https://deliclabs.com/
Stay curious and take it easy!
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BTS #54 Jonathan Mintle aka Botanichemist on Solventless Hash and Rosin Making
In this behind-the-scenes conversation we join Jonathan Mintle, aka Botanichemist, to talk about solventless Cannabis extracts. We spent nearly 3 hours going over every bit of nuance that someone might need to understand if they intend on getting into solventless hash or rosin production. We discuss important considerations that affect final product quality, how to evaluate Cannabis resin trichomes in the context of hashmaking, why different sized micron filters matter in hash production, what it takes to make high quality rosin, and a lot more!
This 3 hour conversation was cut for time. Hear the whole conversation at www.patreon.com/CuriousAboutCannabis
Learn more about Botanichemist Consulting at http://botanichemist.com
Hope you enjoy! Stay curious and take it easy!
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BTS #43 Murphy Murri (Returns!) on CRC, Color in Extracts, Concentrate Remediation
In this behind-the-scenes conversation we are rejoined with extraction technologist and Cannabis educator Murphy Murri to talk all about CRC aka “Color Remediation Cartridges”. CRC has gained a lot of buzz, both positive and negative, in recent years as extractors experiment with refinement techniques that manipulate the appearance of the extract. The concept of “colorless” Cannabis extracts was largely popularized by The Clear years ago, and now has become commonplace. But what is CRC? And what is happening to these extracts when their color is “remediated”? And does CRC present any risks to consumers or extraction technicians?
Murphy Murri provides a common sense take on CRC for anyone wanting to wrap their minds around this popular topic.
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