Cannabis and Cannabinoid Research

BTS #36 Anna Schwabe PhD on Sources of Variation in Cannabis Plants, Hope for Indica/Sativa?

In this behind-the-scenes episode we join Anna Schwabe, PhD, a geneticist and plant scientist that spent her PhD work examining how and why Cannabis plants exhibit different chemical profiles, smells, and effects. In our conversation we dive into many of these nuances and talk about whether people can distinguish Cannabis varieties consistently by smell, how much variation exists between Cannabis plants labeled as the same strain, and whether there may be some hope after all for the colloquial use of the terms “indica” and “sativa”.

Learn more about Anna’s work at www.annaschwabe.com

BTS #35 Vincenzo Di Marzo, PhD on the Endocannabinoid System and the Endocannabinoidome

In this behind-the-scenes episode we join renowned endocannabinoid researcher Dr. Vincenzo Di Marzo, who has been studying endocannabinoids since their discovery in the late 1980s and 1990s. Dr. Di Marzo, along with his colleagues, originally proposed the concept of the endocannabinoid system, the entourage effect, and the endocannabinoidome. Currently Dr. Di Marzo is working on studying the relationships between endocannabinoids and the gut microbiome to better understand how cannabinoids may affect health through the gut. In our conversation we discuss Dr. Di Marzo’s fascination with endocannabinoids, how he conceptualizes the endocannabinoidome, common misunderstandings about endocannabinoids, how the concept of the “entourage effect” has evolved away from its original intended meaning, where the future of Cannabis research may be heading, and much more.

This was a career highlight of mine to be able to talk to Vincenzo and I am honored to share this conversation with you. Enjoy!

BTS #32 Mark Scialdone PhD on Cannabis Chemistry History, Hydrogenated Cannabinoids, Science and Art

In this behind-the-scenes episode we sit down with Mark Scialdone PhD, a chemist responsible for inventing hydrogenated cannabinoid acids, semi-synthetic cannabinoids that could be effective at battling certain types of cancer. We discuss the history of cannabinoid science, controversy around cannabinoid boiling points, how Mark learned from his research with catnip essential oil hydrogenation and how he adapted the technology for Cannabis essential oil, the importance of balancing science with art, the future of Cannabis research, his role in helping the American Chemical Society’s Cannabis Chemistry subdivision get started, and much more.

This episode was cut for time. To listen to the extended 2+ hour version, visit www.Patreon.com/CuriousAboutCannabis

BTS #31 The Doctors Knox on the Endocannabinoid System and Revolutionizing Healthcare

In this behind-the-scenes conversation we speak with The Doctors Knox, aka The Knox Docs, including Drs. Janice, David, Rachel, and Jessica Knox to talk all about the endocannabinoid system and how our understanding of the endocannabinoid system and the endocannabinoidome is revolutionizing healthcare.

This was our first interview with four people at the same time, so it was quite a different experience and allowed for some unique dynamics that I hope you enjoy.

You can learn more about The Doctors Knox at https://doctorsknox.com/

BTS #29 Kyle Boyar on Microbiological Testing, Cannabinoid Hyperemesis Syndrome, LIMS

In this behind-the-scenes episode we sit down with Kyle Boyar, vice chair and scholarship chair for the Cannabis Chemistry subdivision of the American Chemical Society and Director of Product Science at TagLeaf. We talked about the ways Cannabis testing labs test Cannabis samples for microbiological contaminants, how microbiological testing can go wrong, other issues facing Cannabis testing, controversy around a medical condition called Cannabinoid Hyperemesis Syndrome (CHS), and more!

This conversation was cut to fit our new 1.5 hour limit. To listen to the entire 2 hour conversation, join our community on Patreon at www.Patreon.com/CuriousAboutCannabis

Enjoy and stay curious!

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BTS #28 Jacqueline von Salm PhD on Cannabis Terpenes, Drugs From Nature, Chemical Ecology

In this behind-the-scenes episode we sit down with organic chemist Jackie von Salm PhD (@terp_queen_phd on Instagram), who was a recent winner of the ElSohly award given to outstanding researchers in the Cannabis space. Her team recently discovered the presence of a terpene common only among certain varieties of Cannabis, which is not tested for currently among most Cannabis testing labs and has largely been excluded from the discussion when talking about categorizing Cannabis varieties by chemical profile. We also discuss the process of discovering natural products suitable for drug development, how chemistry is interconnected with ecology and psychology, what she wants to see from future Cannabis research and much more!

Jackie is a co-founder and CSO of the company Psilera Bioscience which is dedicated to exploring the potential of psychoactive natural products to treat mental health disorders.

Learn more about Psilera Bioscience at www.psilera.com

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BTS #26 Dr. Genester Wilson-King on Cannabis and Hormones, Women’s Health, Inequities in Healthcare

In this behind-the-scenes episode we talk with Dr. Genester Wilson-King, a board certified OB/GYN, Cannabis clinician, and hormone expert. Our conversation spanned many topics including how cannabinoids and hormones interact with one another, how Cannabis affects women differently than men, how Cannabis affects women after menopause differently than women experiencing cyclical hormones, how Cannabis affects cis gender people different than trans gender people, how Cannabis affects fertility, Cannabis during pregnancy and breastfeeding and much more!

Learn more about Dr. Wilson-King here: https://www.victoryrejuvenationcenter.com/

Enjoy and stay curious!

BTS #20 Linda Klumpers PhD on Cannify, Cannabinoid Pharmacology, Cannabis for Pain

In this behind-the-scenes (BTS) episode we sit down with Dr. Linda Klumpers, a clinical pharmacologist that has been studying how Cannabis and cannabinoids affect the body. Our conversation covered a lot of topics including how cannabinoids affect the body, clinical evidence for the entourage effect, how Cannabis affects pain and sleep, misconceptions about Cannabis, differences between studying Cannabis in the Netherlands versus the United States, and more!

Besides the clinical cannabinoid research that she is involved with, Dr. Klumpers is also the mind behind Cannify, a quiz that helps connect people to peer-reviewed human clinical data about Cannabis. Learn more about Cannify by going to www.Cannify.us

BTS #19 Dr. Junella Chin on Medical Uses of Cannabis, Pediatric Use, Women’s Health

In this behind-the-scenes (BTS) episode we talk with Dr. Junella Chin, a physician that has specialized in Cannabis and cannabinoid medicine. Our conversation spanned a variety of topics including pediatric Cannabis use, how Cannabis interacts with sexual hormones like estrogen and testosterone, how people of different ethnicities respond differently to Cannabis, the state of cannabinoid education in the modern healthcare system, and more!

You can learn more about Dr. Junella Chin by visiting www.DrJuneChin.com

BTS #18 Kevin McKernan of Medicinal Genomics on Cannabis Genetics, GMO Cannabis, Pest Resistance

In this behind-the-scenes (BTS) episode we sit down with Kevin McKernan, the founder of Medicinal Genomics, who has been working for years on mapping and understanding the Cannabis genome. Our 2 hour conversation spanned many topics including basic misunderstandings about genetics, the genes responsible for cannabinoid production in Cannabis, how genes sometimes do unexpected things, how Cannabis genes are related to pest resistance, philosophical and ethical issues related to genetic modification of organisms and much more.

The pre-print research article referenced in this conversation can be found here: https://www.medicinalgenomics.com/breakthrough-cannabis-genomics-study/

Medicinal Genomics: www.medicinalgenomics.com

Kannapedia: www.kannapedia.net

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