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Cannabis Testing Gone Wrong? (IV) feat. Kyle Boyar

Do we even test for the right things?

Now that medical and adult-use cannabis programs have been around for some time, and with them mandated lab testing of products – we have a lot of data that we can begin to review in order to assess how well we are managing the quality of cannabis in the market.

In this episode we are joined by microbiologist and analytical technologist Kyle Boyar to confront the idea that there may be some things that regulators require testing for that will almost never show up in a sample, while there are certain toxins that show up more often than we might expect which are NEVER required for testing in any state in the country.

What’s going on? Let’s dive in and find out!

Cannabis Testing Gone Wrong? (Part III) feat. Dr. Josh Swider of Infinite Chemical Analysis Labs

Continuing our series on the issues facing the Cannabis testing industry, we sit down with Josh Swider of Infinite Chemical Analysis Labs to discuss the ways that he and his lab have felt the effects of potency inflation and lab shopping over the past several years. One by one Josh has watched clients disappear after complaints that his THC potency numbers were not high enough compared to his competitors. This is a story all too familiar to most labs that have ever operated in the space. Eventually the requests to boost THC results became much more direct as clients started offering bribes including outright briefcases full of cash. When he denied these advances, he began receiving death threats.

In an effort to understand just how bad the problem was, Josh and his team began collecting products off the shelf and testing them in the lab to see how the results compared to the original test results on record for the product. The results were alarming. Not only did he find evidence of potency fraud, but he also ended up finding evidence of various contaminants in products that somehow originally tested “clean.”

In this episode Josh and I take time to discuss his journey, how the industry has gotten into the situation it is in, and some potential solutions for moving the industry in a positive direction.

Learn more about iCAL: https://infinitecal.com/

Cannabis Testing Gone Wrong (II) feat. Josh Smith of Therapeutic Health Choice Labs

In this extended 2+ hour episode, Josh Smith of Therapeutic Health Choice, an analytical lab based out of Michigan, takes us on a deep dive into his experiences of Cannabis testing fraud as we explore some potential ways to fix issues like lab shopping and bring scientific integrity back to the cannabis industry.

About Josh:

Josh Smith is a seasoned biotech executive with a graduate degree in Clinical Microbiology and over 24 years of experience in biotechnology, molecular biology, and pharmaceutical R&D. He has played a key role in pioneering various projects, including founding Premium CBD Labs and later Vardera Inc., where he built a nationally recognized laboratory network from the ground up. His work has led to several molecular biology patents, and he has served as an expert witness in legal cases across Wisconsin, Illinois, and Michigan.

Josh is actively involved in shaping industry standards through his participation in international method committees like AOAC and ASTM. He has also lobbied in Wisconsin, advocating for improved policies in the lab testing industry. In late 2023, he was part of the team that successfully overturned the compliance testing requirement for Aspergillus spp. in the state of Oregon.

Beyond his corporate roles, Josh is passionate about advancing scientific knowledge and innovation. He serves on the Curriculum Advisory Board for the graduate-level Cannabis Applied Science Program at Fanshawe College (London, ON), is a member of the Cannabis Science and Research Organization (Oregon), and is an editor for the Cannabis and Psychedelic Science Journal.

Cannabis Testing Gone Wrong (Part I) with Yasha Kahn of MCR Labs

This is the first of a series of conversations with lab owners and industry experts revolving around the topic of fraud, mismanagement, and poor regulations facing Cannabis testing labs. With issues ranging from THC potency inflation, under-reporting of contaminants, perverse incentive structures promoted by regulations, market manipulation, and more – this series dives deep into a very controversial issue to try to understand the problem at its foundation and find meaningful and practical solutions forward to restore trust and bring greater transparency to the Cannabis industry.

Yasha Kahn is one of the co-founders of MCR Labs and spends much of his time diving into data. Over the past several years, Yasha has been on a mission to collect publicly available Cannabis testing data and make it accessible to the industry in hopes of promoting fruitful research, discussion, and regulatory changes to positively impact the industry. In this episode we dive into some of the data that Yasha has gathered and start to unpack the story that it tells.

Link to the raw data: https://drive.google.com/drive/folders/1IIlgudS3b1rvxbupeMaR_BdeUQmz3pOZ?usp=drive_link

CBD and the CB1 Receptor: A Look at Allosteric Modulation with Rob Laprairie, PhD + Liz Thompson, MS | #102

How does CBD affect the CB1 receptor, really?

Rob Laprairie is a cannabinoid researcher out of the University of Saskatchewan who was involved in the discovery of CBD’s allosteric binding activity on the CB1 receptor – leading to a host of speculative theories about how CBD influences the activity of THC. In this conversation, continuing our Train with Mary Jane series, we sit down with Rob and discuss his work studying the CB1 receptor to better understand how CBD and “minor” cannabinoids from Cannabis affect the body. Rob helps break down common misunderstandings about CBD’s effects, explains how our understanding of chemical receptors is evolving, and what the future of cannabinoid research may look like.

“Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors”: https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14440

Hidden Threats: Exploring Viruses and Viroids with IPM Specialist Matthew Gates | #101

In this episode we sit down with Integrated Pest Management (IPM) specialist Matthew Gates to delve into the often-overlooked world of cannabis viruses and viroids. In this episode, Matthew brings his extensive expertise to the table, shedding light on the insidious pathogens that can silently wreak havoc on cannabis crops.

As the cannabis industry continues to grow and evolve, understanding the hidden threats posed by viruses and viroids becomes paramount. Matthew explains the various types of viruses and viroids that can affect cannabis plants, their symptoms, and the potential economic impact on growers. He also shares insights into the latest research and diagnostic techniques that can help detect these pathogens early, enabling proactive management and prevention.

But it’s not all doom and gloom. Matthew provides practical, actionable advice on how to implement effective IPM strategies to mitigate the risks. From cultural practices to biological controls and cutting-edge technologies, he covers a comprehensive range of tools and methods that can help protect your cannabis crop and ensure its health and productivity.

Whether you’re a seasoned cultivator, a novice grower, or simply interested in the science behind cannabis cultivation, this episode is packed with valuable information that you won’t want to miss. Tune in to gain a deeper understanding of the challenges posed by cannabis viruses and viroids and learn how to safeguard your plants against these unseen adversaries.

Learn more about Matthew at www.zenthanol.com

HHC, THCP, and Beyond with Westley Cruces of Colorado Chromatography

You may have noticed that your local gas station has started selling products marketed like Cannabis products with promises that they are legal ways to get you high without THC. No, we haven’t gone back in time. This isn’t 1999 and no, you’re not reading one of those “legal bud” ads in the back of the High Times magazine. This is 2024 and we are seeing a re-emergence of synthetic cannabinoids, particularly THC analogues, now presumably legal under the guise of the 2018 Farm Bill.

Colorado Chromatography is one of the leading labs responsible for producing and studying these new cannabinoids on the block, like HHC, H4CBD, THCP, and others. In this conversation we sit down with the Chief Science Officer of and co-founder of Colorado Chromatography, Westley Cruces, to talk about their journey learning about these molecules, the results from preliminary safety studies on HHC, evidence of fraud in delta-8 and THCP products, and more!

Learn more about Colorado Chromatography: https://coloradochromatography.com/

Is Acetone Lurking in Your Terpenes? and Other Cannabis Science Musings feat. Jeff Raber, PhD

We kick off 2024 catching up with Dr. Jeff Raber of The Werc Shop to talk about Cannabis quality, Cannabis potency testing fraud, THC inflation, acetone showing up in Cannabis extracts, preparing young scientists for working in the Cannabis industry, the launch of The Werc Shop’s ENTOUR brand and more!

How do we fix the lab testing fraud issue in the Cannabis industry?

Why is acetone showing up in terpene-rich Cannabis samples?

How can young scientists prepare for the brutal realities of working for a startup Cannabis company?

We explore these questions and more in this episode of The Curious About Cannabis Podcast!

Learn more about ENTOUR at www.entourbrand.com

Learn more about The Werc Shop at www.thewercshop.com

Photoperiods, Flushing, and the Science of Dense Buds with Michael Alden of Clemson University

12/12 photoperiods for flowering? Flushing for better flower? Eh, you might have been misled.

In this episode we meet Michael Alden, a researcher at Clemson University in South Carolina who has spent several years carefully examining how the Cannabis plant responds to inputs, stress and different cultivation techniques. He shares with us his findings so far regarding the science behind nutrient flushing, why 12/12 flowering photoperiods are not ideal for some plants, how to achieve dense buds without the use of plant growth regulators, and much more!

If you are interested in the science behind Cannabis cultivation – you’ve come to the right place.

#CuriousAboutCannabis #Cannabis #CannabisCultivation #CannabisGrowing #HempCultivation #HempGrowing #Flushing #PGRs #nutes #botany #horticulture #CannabisEducation #HempEducation #CannabisPodcast #CannabisScience

The Science Behind CBG: A Pharmacist’s Perspective with Codi Peterson PharmD MS

Explore the fascinating world of Cannabigerol (CBG) in the latest episode of our podcast! We are joined by our friendly neighborhood pharmacist – Dr. Codi Peterson. As we delve into the hot topic of CBG, we cover its effects on the body and compare it to other medications. We also take an unexpected detour to discuss the influence of AI like ChatGPT in Cannabis education. Join us as we ponder the future of Cannabis content, engage in lively conversation, and learn a lot more about this promising cannabinoid. Tune in now!

#CBG #CannabisCommunity #Cannabinoids #HempProducts #PharmacyInsights #CannabisEducation #ChatGPT #FutureOfCannabisContent #CannabisPodcast #CuriousAboutCannabis #CodiPeterson #JasonWilsonMS #HempScience #Cannabigerol #CannabisIndustry #CannabisCommunity

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