CBD, Pain and Opioids: Bringing Translational Research to Cannabis with Maria T Rivera-Garcia PhD | BTS 86
By cacpodcast.comIn this behind-the-scenes interview we talk with Dr. Maria T Rivera-Garcia about her research investigating the effects of CBD-rich whole plant extract vapor on pain and opioid reward seeking behavior in female rats in a study titled, “High-CBD Cannabis Vapor Attenuates Opioid Reward and Partially Modulates Nociception in Female Rats”.
While on the surface this may seem like a simple study about how CBD influences opioid use – there is actually a lot more going on here. First of all this study utilized female rodents, which is very uncommon. The vast majority of preclinical rodent research uses male rodents almost exclusively due to reasons we unpack during the episode. This has led to a gross under-representation of sex differences in biomedical research.
Second, Maria and colleagues decided to utilize the vapor of whole plant CBD-rich Cannabis extract rather than using CBD isolate that is often diluted and injected, ultimately leading to results that do not accurately reflect real-world situations.
Together, these two decisions point to a common theme that is woven into this research study – scientists need to focus on doing research that better represents the real world. The results from this study are fascinating, so get your notebook ready and let’s dive in!
Link to the study: https://www.sciencedirect.com/science/article/pii/S2772392522000451
About Maria:
Maria Teresa Rivera-Garcia has a major in psychology and a minor in neuroscience from the National Autonomous University of Mexico, where she started defining her academic interests towards the study of neurobiological mechanisms of addiction. After undergrad, Maria did a Master and a PhD in Neuropharmacology and Experimental Therapeutics, her research focused on the neurochemical effects of solvent inhalation and its relation with the development of psychosis. Maria moved to the US in 2016 to pursue her postdoctoral training in the Oregon and Health and Science University, studying sex and age differences in dopaminergic function and how this is related to psychiatric illnesses, including addiction. In 2020, Maria joined Legacy Research Institute to complete her second postdoctoral stay under the guidance of Dr. Adie R. Wilson-Poe, where she studied the pharmacological interaction between opioids and cannabinoids in pain-oriented models. Recently, Maria got accredited as Qualified Mental Health Provider and became a member of the Cascadia Health clinicians team, currently providing services within the Child and Family Program.
#CannabisEducation #CBD #CBDOil #WholePlantExtract #WholePlant #FullSpectrum #BroadSpectrum #Hemp #HempExtract #MedicalCannabis #Addiction #MentalHealth #Opioids #CuriousAboutCannabis
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Living Authentically and Casually Baked with Johanna Nuding | BTS 85
Johanna Nuding left everything she knew in her home state of Texas behind to rediscover herself as she lived abroad in a foreign country. Normally equipped with the strong communication skills typical of a marketing professional – for this journey, Jo would have to lose her ability to communicate. After a powerful series of life lessons, Johanna moved from Italy to California to begin a new chapter of life committed to a promise of living authentically. And with that authenticity – came the Casually Baked podcast. In this behind-the-scenes conversation we meet up with Jo to talk about her personal journey with Cannabis and how, upon returning to the United States with a newfound appreciation for the ability to communicate effectively, Johanna set out on a mission to use her skills as a storyteller and media creative to help people navigate the confusing world of Cannabis.
Along with the Casually Baked podcast, Johanna, with the help of a PhD friend, also has a line of Cannabis topicals that are in development and designed to help people with sensitive skin, including eczema, that may have trouble using common Cannabis skincare products on the market.
To learn more about Casually Baked, visit: https://casuallybaked.com/
To learn more about MJ Skin Relief, visit: https://mjskinrelief.com/
Stay curious and take it easy!
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Infusing Cannabis Education with Curated Interactive Events with Tamara Anderson of Culinary & Cannabis | BTS 84
In this behind-the-scenes conversation we meet Tamara Anderson, a nurse by day and Cannabis event curator by night. Through a series of seemingly divinely orchestrated life events, Tamara realized that their skills as a nurse and pastry chef were perfectly suited to help people understand the many different ways that Cannabis can be used and how those products can affect the body.
Through personalized curated events ranging from luxurious spa experiences to 5-star chef-cooked infused meals at home – Tamara goes out of their way to ensure that anyone can have the chance to experiment with Cannabis edibles, topicals and other products so that they can figure out what kind of relationship, if any, they want with Cannabis.
In our conversation we discuss the role of experiential learning in Cannabis education and why it is so important for people to gain hands-on experience with Cannabis and Cannabis derived products when trying to learn about them. We also discuss the ways in which Tamara’s curated events have impacted some of their attendees, how Cannabis education affects Cannabis stigma, and more!
Learn more about Culinary and Cannabis at: https://www.culinaryandcannabis.com/
#CannabisEducation #CuriousAboutCannabis #CannabisEdibles #Hemp #CannabisEvents #CannaSpa #CulinaryAndCannabis
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Standards: The Final Frontier? ASTM Intl’s Effort to Standardize the Cannabis Industry with Darwin Millard (The Spock of Cannabis) | BTS 83
In this behind-the-scenes conversation I beam aboard the USS Cannabis starship to join “The Spock of Cannabis” Darwin Millard to talk about ASTM International’s efforts to bring the planet together to develop unifying standards for the Cannabis industry. In this conversation we talk about why the development of international quality standards is critical, how ASTM’s collaborative open-door process of standard development is unique compared to how other organizations or government agencies develop standards, and how everyone with any interest in Cannabis has been invited to join the table to lend a voice and help drive the future of the international Cannabis industry.
You can learn more about ASTM International’s Cannabis subcommittee and get involved here: https://www.astm.org/get-involved/technical-committees/committee-d37
You can learn more about Darwin’s work at thespockofcannabis.com
“Live Long and Process!” – The Spock of Cannabis
#CannabisEducation #CannabisQuality #Cannabis #Hemp #CannabisIndustry #HempEducation #GlobalCannabis #GlobalCannabisIndustry #ASTM #ASTMIntl #LiveLongAndProcess #CuriousAboutCannabis
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Unraveling the DNA of Cannabis with Oussama Badad of Trilogene Seeds | BTS 82
In this behind-the-scenes episode I chat with Oussama Badad, the lead geneticist for Trilogene Seeds to talk about the science behind Cannabis genetics and gene editing technologies. We discuss common misconceptions around gene editing, how gene editing using tools like CRISPR and RNA interference is different than the genetic modification technologies used to produce GMOs, how gene edited Cannabis plants could affect the Cannabis industry, Trilogene Seeds’ quest to produce THC-free hemp plants, Cannabis tissue culturing, and much more.
Learn more about Trilogene Seeds at trilogeneseeds.com
#CannabisEducation #CannabisGenetics #Cannabis #Hemp #THCFree #CannabisPodcast #CuriousAboutCannabis
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We Grow Cannabis: Uniting Community Through Marijuana Horticulture with Jorge Cervantes | BTS 81
In this behind-the-scenes interview we meet up with legendary Cannabis cultivator, educator and author Jorge Cervantes. We talk about his new book We Grow Cannabis, his mission to update and revise the classic Cannabis grower’s bible Marijuana Horticulture, how Cannabis cultivation has changed over the years, common mistakes new Cannabis growers make, the problem with fertilizers, how to start growing organically, and more!
Learn more about Jorge’s work and download a free copy of We Grow Cannabis at:
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Harnessing AI for Sustainable Agriculture and Cannabis Education with Matthew Gates | BTS #80
In this behind-the-scenes conversation we drop in with integrated pest management specialist Matthew Gates to talk about his thoughts for this upcoming pest season before we spin off into a philosophical conversation about the impacts of AI and other technological advancements on Cannabis science education, regenerative agriculture, and more! We also throw in some anime references along the way to make for a great conversation.
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This is Matthew’s third appearance on the podcast. If you are new to Matthew’s work, I recommend going back to listen to his first two episodes (BTS #68 and BTS #71) on the podcast to learn a ton about some of the science associated with integrated pest management and Cannabis cultivation.
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Matthew’s consulting services: https://www.zenthanol.com
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Zenthanol YouTube channel: https://www.youtube.com/@Zenthanol
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What’s In a Toke? Exploring the Chemistry of Cannabis Smoke and More with Dr. Riley Kirk | BTS #79
Why does smoking Cannabis deliver unique effects compared to vaping or ingesting Cannabis? Why are social media platforms banning Cannabis educators from talking about the science of Cannabis? We have questions!
In this behind-the-scenes episode I sat down with Dr. Riley Kirk (@cannabichem) from Real Isolates, the company behind the Cannabis smoke extract product called Smokenol, to talk about the chemistry of Cannabis smoke (and lots of other cool natural products science!). In this conversation we discuss some of the unique cannabinoids that show up in Cannabis smoke and what Dr. Kirk has learned during her time studying the transformations of cannabinoids like CBD.
We also discussed her struggle to share Cannabis science education with the world due to the antagonistic nature of social media toward Cannabis content. Dr. Kirk has been shadow banned and de-platformed from social media sites like Instagram and TikTok for discussing basic Cannabis science and cannabinoid pharmacology. We dive into why these issues have real-world adverse effects for anyone curious about Cannabis and what Cannabis educators should know before they rush to their Reels or Stories to talk about Cannabis.
The conversation rounds off with a dive into Dr. Kirk’s love for plants where we talk about her favorite non-Cannabis medicinal plants and the exciting things we can learn when we apply the lens of Cannabis science to other natural products.
Profound Naturals: https://www.profoundnaturals.com/
Smokenol: https://smokenol.com/
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Cannabis Quality is More Than THC or Terpenes with Adie Rae PhD | BTS #78
What does Cannabis quality mean to you? Is it all about THC? Is it all about the terps?
In this behind-the-scenes episode we caught up with pharmacologist and researcher Dr. Adie Rae from Oregon, USA to talk primarily about the results of her recent publication “The Nose Knows: Aroma, but Not THC Mediates the Subjective Effects of Smoked and Vaporized Cannabis Flower” which revealed that subjective aroma enjoyment correlates more with positive Cannabis experiences than THC or terpene concentrations. We also discussed Dr. Rae’s prior and current research on the interactions between the endocannabinoid system and opioids, the need to re-evaluate how we define “quality” in the Cannabis industry, the importance of organoleptic training for medicinal herbs, and more!
Adie Rae is a neuroscientist known for her extensive expertise on cannabis. She is an Assistant Scientist at Legacy Research Institute, and adjunct faculty at Washington State University. Her human and preclinical research is focused on pain management, addiction, and harm reduction. Adie has published in top academic journals under the surname Wilson-Poe, and she is passionate about the interaction between cannabis and opioids. Adie serves as the Vice-Chair of the Oregon Cannabis Commission, and she is a long-standing member of the International Cannabinoid Research Society. Dr. Rae also co-founded the consulting and technology firm Smart Cannabis. Follow her on Instagram: @dr.adie
You can learn more about Dr. Rae and her work at https://www.smartcannabis.life/
Link to “Nose Knows” study: https://www.mdpi.com/2813-1851/1/2/8
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The Science of the Cannabis Plant with Allison Justice PhD | #77
In this behind-the-scenes episode we meet plant scientist Dr. Allison Justice. Dr. Justice is the founder of the vertically integrated hemp company The Hemp Mine, located in South Carolina. She is also the founder of the Cannabis Research Coalition – a research organization formed in partnership with Clemson University that is dedicated to pursuing practical agricultural research on Cannabis to provide answers relevant for farmers, extractors and product manufacturers.
In this conversation we explore Allison’s own research into the Cannabis plant, ranging from studies on light intensity, photosynthetic rates, harvest techniques, drying parameters, curing and more. We also discuss the challenges that Cannabis cultivators in the southeastern United States are facing when trying to utilize plants sourced from places with very different climates like California, Oregon or Colorado.
We cover a lot of ground in a short amount of time, so get ready to take notes, buckle up, and let’s learn together!
The Hemp Mine: https://www.thehempmine.com
Cannabis Research Coalition: https://www.cannabisrc.org/
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