Cannabis Safety

The Science Behind CBG: A Pharmacist’s Perspective with Codi Peterson PharmD MS

Explore the fascinating world of Cannabigerol (CBG) in the latest episode of our podcast! We are joined by our friendly neighborhood pharmacist – Dr. Codi Peterson. As we delve into the hot topic of CBG, we cover its effects on the body and compare it to other medications. We also take an unexpected detour to discuss the influence of AI like ChatGPT in Cannabis education. Join us as we ponder the future of Cannabis content, engage in lively conversation, and learn a lot more about this promising cannabinoid. Tune in now!

#CBG #CannabisCommunity #Cannabinoids #HempProducts #PharmacyInsights #CannabisEducation #ChatGPT #FutureOfCannabisContent #CannabisPodcast #CuriousAboutCannabis #CodiPeterson #JasonWilsonMS #HempScience #Cannabigerol #CannabisIndustry #CannabisCommunity

Seeing Through The Smoke: Separating Cannabis Facts from Fiction with Peter Grinspoon, MD | BTS 92

In this behind-the-scenes episode we catch up with physician and medical Cannabis educator Peter Grinspoon, MD to talk about the ways in which Cannabis is misunderstood – both by the anti-Cannabis camps and the pro-Cannabis camps. We talk about the clinical data around medical Cannabis, what issues Cannabis has demonstrated efficacy in treating, the limitations of medical Cannabis and more.

We also spend some time diving into Peter’s background, talking about his late father Lester Grinspoon, MD who authored a landmark book entitled Marihuana Reconsidered which was published in 1971 and paved the way for the medical Cannabis movements that would follow. We also discussed Peter’s brother Danny’s struggle with cancer, which claimed his life at the age of 15, and the role Cannabis played in enhancing Danny’s quality of life before he died. Later in life Peter would struggle with a grueling opiate addiction which he would later go on to write about in his 2016 book Free Refills: A Doctor Confronts His Addiction. Toward the end of the show we talk about what it was like growing up around famed scientist and science communicator Carl Sagan, who was a good friend of the Grinspoon family and also a Cannabis user.

Peter just released a new book entitled Seeing Through The Smoke: A Cannabis Specialist Untangles The Truth About Marijuana available now.

This was a special episode for me, personally, because Peter’s work, the work of his father, and the work of Carl Sagan all had big impacts on how I came to think about Cannabis and science education. I hope you enjoy!

#CannabisEducation #MedicalCannabis #MedicalMarijuana #CannabisIndustry #CannabisCommunity #Cannabinoids #Addiction #CarlSagan #LesterGrinspoon #PeterGrinspoon #Cancer

The Quest for the CB3 Receptor and Beyond with Viola Brugnatelli, PhD | BTS 89

Is there a CB3 receptor?

In this episode we catch up with Italian endocannabinoid system researcher and neuropharmacologist Viola Brugnatelli, PhD to discuss her work investigating the activity of orphaned G-protein coupled receptors (GPCRs) like GPR55, GPR18, GPR92, and others.

We also discuss Viola’s decision to focus her energy on educating the healthcare community and others about the science of Cannabis through her company Cannabiscientia which just published a great resource for health care providers called The Principles of Clinical Cannabinology.

To learn more about Cannabiscientia, visit https://cannabiscientia.com/

#cannabis #cannabinoids #cb3 #ecs #endocannabinoidsystem #cannabiscientia #cannabisscience #cannabinoidpharmacology #medicalcannabis #medicalmarijuana #curiousaboutcannabis

Cannabis and the Convergence of Neurodivergence with Miyabe Shields PhD | BTS 87

Disclaimer: In this episode, we discuss some heavy topics that touch on mental health struggles and suicidal ideation. None of the information in this episode or any other Curious About Cannabis episode should be considered medical advice. All of our content is for educational and entertainment purposes only.

In this raw behind-the-scenes episode I had the chance to catch up with endocannabinoid system researcher and science communicator Miyabe Shields, PhD. We spent much of our time together discussing the convergence of Cannabis, mental health, and neurodivergence – addressing many of the taboos and social stigmas associated with altering consciousness and treating the mind with Cannabis.

This is almost certainly just the beginning of a series of conversations that Miyabe and I will be having as we continue to unpack their fascination with the endocannabinoid system and natural products science – so stay tuned for more!

#Cannabis #CannabisResearch #Neurodiversity #Neurodivergent #Spectrum #Consciousness #CannabisEducation #MedicalCannabis #CannabisForMentalHealth #Psychology #NaturalProducts #CuriousAboutCannabis

CBD, Pain and Opioids: Bringing Translational Research to Cannabis with Maria T Rivera-Garcia PhD | BTS 86

In this behind-the-scenes interview we talk with Dr. Maria T Rivera-Garcia about her research investigating the effects of CBD-rich whole plant extract vapor on pain and opioid reward seeking behavior in female rats in a study titled, “High-CBD Cannabis Vapor Attenuates Opioid Reward and Partially Modulates Nociception in Female Rats”.

While on the surface this may seem like a simple study about how CBD influences opioid use – there is actually a lot more going on here. First of all this study utilized female rodents, which is very uncommon. The vast majority of preclinical rodent research uses male rodents almost exclusively due to reasons we unpack during the episode. This has led to a gross under-representation of sex differences in biomedical research.

Second, Maria and colleagues decided to utilize the vapor of whole plant CBD-rich Cannabis extract rather than using CBD isolate that is often diluted and injected, ultimately leading to results that do not accurately reflect real-world situations.

Together, these two decisions point to a common theme that is woven into this research study – scientists need to focus on doing research that better represents the real world. The results from this study are fascinating, so get your notebook ready and let’s dive in!

Link to the study: https://www.sciencedirect.com/science/article/pii/S2772392522000451

About Maria:

Maria Teresa Rivera-Garcia has a major in psychology and a minor in neuroscience from the National Autonomous University of Mexico, where she started defining her academic interests towards the study of neurobiological mechanisms of addiction. After undergrad, Maria did a Master and a PhD in Neuropharmacology and Experimental Therapeutics, her research focused on the neurochemical effects of solvent inhalation and its relation with the development of psychosis. Maria moved to the US in 2016 to pursue her postdoctoral training in the Oregon and Health and Science University, studying sex and age differences in dopaminergic function and how this is related to psychiatric illnesses, including addiction. In 2020, Maria joined Legacy Research Institute to complete her second postdoctoral stay under the guidance of Dr. Adie R. Wilson-Poe, where she studied the pharmacological interaction between opioids and cannabinoids in pain-oriented models. Recently, Maria got accredited as Qualified Mental Health Provider and became a member of the Cascadia Health clinicians team, currently providing services within the Child and Family Program.

#CannabisEducation #CBD #CBDOil #WholePlantExtract #WholePlant #FullSpectrum #BroadSpectrum #Hemp #HempExtract #MedicalCannabis #Addiction #MentalHealth #Opioids #CuriousAboutCannabis

Standards: The Final Frontier? ASTM Intl’s Effort to Standardize the Cannabis Industry with Darwin Millard (The Spock of Cannabis) | BTS 83

In this behind-the-scenes conversation I beam aboard the USS Cannabis starship to join “The Spock of Cannabis” Darwin Millard to talk about ASTM International’s efforts to bring the planet together to develop unifying standards for the Cannabis industry. In this conversation we talk about why the development of international quality standards is critical, how ASTM’s collaborative open-door process of standard development is unique compared to how other organizations or government agencies develop standards, and how everyone with any interest in Cannabis has been invited to join the table to lend a voice and help drive the future of the international Cannabis industry.

You can learn more about ASTM International’s Cannabis subcommittee and get involved here: https://www.astm.org/get-involved/technical-committees/committee-d37

You can learn more about Darwin’s work at thespockofcannabis.com

“Live Long and Process!” – The Spock of Cannabis

#CannabisEducation #CannabisQuality #Cannabis #Hemp #CannabisIndustry #HempEducation #GlobalCannabis #GlobalCannabisIndustry #ASTM #ASTMIntl #LiveLongAndProcess #CuriousAboutCannabis

Cannabinoid Science: Past, Present and Future (Southern Oregon University Lecture, 2021)

The history of cannabinoid science tells a fascinating story that many people are really unfamiliar with. In this lecture, which I gave for Southern Oregon University back in October of 2021, I chart some of the basic series of events that led to the discovery of CBD, THC, cannabinoid receptors, the endocannabinoid system, and the endocannabinoidome.

The video associated with this lecture is available on the Curious About Cannabis YouTube at http://www.youtube.com/@curiousaboutcannabis

The 2023 Curious About Cannabis Master Class is coming up! Spend 6 months diving into a Cannabis science crash course with me and over a dozen special guests! Register today at http://www.masterclasscannabis.com

How Do Testing Labs Boost THC Numbers? | Lecture by Jason Wilson MS

45% THC Flower?!

It is a well known issue in the Cannabis industry that some Cannabis testing laboratories boost THC numbers to make clients happy and gain market share over other laboratories. This has led to ridiculous THC values on Cannabis product labels. Although this issue is well known, it does not ever seem to get adequately addressed. In this video, Cannabis testing veteran Jason Wilson MS explains the many ways labs can intentionally commit fraud or laboratory mistakes that lead to elevated THC values.

To see the video on YouTube, visit: https://www.youtube.com/watch?v=DUb22BP-RcM

This lecture is an excerpt from the Curious About Cannabis self-paced course on Cannabis Testing Fundamentals available for free at http://learn.cacpodcast.com

You can also learn more about Cannabis testing and quality control in labs by reading the Curious About Cannabis book available on Amazon, Barnes and Noble and other book retailers! Learn more at http://www.curiousaboutcannabisbook.com/

What’s In a Toke? Exploring the Chemistry of Cannabis Smoke and More with Dr. Riley Kirk | BTS #79

Why does smoking Cannabis deliver unique effects compared to vaping or ingesting Cannabis? Why are social media platforms banning Cannabis educators from talking about the science of Cannabis? We have questions!

In this behind-the-scenes episode I sat down with Dr. Riley Kirk (@cannabichem) from Real Isolates, the company behind the Cannabis smoke extract product called Smokenol, to talk about the chemistry of Cannabis smoke (and lots of other cool natural products science!). In this conversation we discuss some of the unique cannabinoids that show up in Cannabis smoke and what Dr. Kirk has learned during her time studying the transformations of cannabinoids like CBD.

We also discussed her struggle to share Cannabis science education with the world due to the antagonistic nature of social media toward Cannabis content. Dr. Kirk has been shadow banned and de-platformed from social media sites like Instagram and TikTok for discussing basic Cannabis science and cannabinoid pharmacology. We dive into why these issues have real-world adverse effects for anyone curious about Cannabis and what Cannabis educators should know before they rush to their Reels or Stories to talk about Cannabis.

The conversation rounds off with a dive into Dr. Kirk’s love for plants where we talk about her favorite non-Cannabis medicinal plants and the exciting things we can learn when we apply the lens of Cannabis science to other natural products.

Profound Naturals: https://www.profoundnaturals.com/

Smokenol: https://smokenol.com/

Catching Up with Murphy Murri on Benzene, Medusa Stones, and Owning the Quality of Your Lab | BTS #75

In this behind-the-scenes episode we caught up with Murphy Murri for an extended discussion about the current state of the Cannabis industry, extraction supply chain quality issues, medusa stones, mushroom extraction and more.

Medusa stones are concentrated lumps of cannabinoids that, rather than having a clear “diamond” appearance, has a chalky appearance. And like you might expect, the “diamond” disintegrates after being handled, turning into a sticky, chalky mess. So what causes the medusa stone phenomenon in Cannabis extracts? During this conversation, Murphy breaks down the phenomenon and the controversy surrounding the hunt for the cause behind these disappointing creations.

Due to some technical difficulties on the day of recording, this discussion was recorded on Zoom instead of our usual platform, resulting in some compromised audio quality.

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